Nucleophilic properties of amines
Amines are nucleophiles The nucleophilic substitution reactions (including mechanisms) of ammonia and amines with haloalkanes to form primary, secondary, tertiary amines and quaternary ammonium salts. The use of quaternary ammonium salts as cationic surfactants. The nucleophilic addition–elimination reactions of ammonia and primary amines with acyl chlorides and acid anhydrides [in new syllabus from 2015]. Students should be able to outline the mechanisms of: • these nucleophilic
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